肠易激综合征(IBS)是一种多种因素引起的、慢性功能性肠道疾病,其临床特点为慢性反复发作的腹痛、腹部不适及排便习惯改变。尽管有各种假说试图阐明IBS的发病机制,但目前尚无单一的发病机制能够解释其所表现的所有症状。近年来,对其发病机制的研究不断增多,认为基因、精神心理因素、饮食、感染、免疫、脑-肠轴等多重因素可复合影响并最终导致内脏高敏、胃肠动力异常而表现出相应的临床症状。本文中作者就目前在该领域的最新进展作一综述。

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