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黄酮类化合物抗胰腺癌作用研究进展
作者:龚龙伟1  周家华2  许茜3 
单位:1. 东南大学医学院, 江苏 南京 210009;
2. 东南大学附属中大医院普外科, 江苏 南京 210009;
3. 东南大学公共卫生学院, 江苏 南京 210009
关键词:胰腺癌 黄酮类化合物 凋亡 细胞周期 胰腺癌干细胞 文献综述 
分类号:R735.9
出版年·卷·期(页码):2013·32·第四期(515-518)
摘要:

黄酮类化合物在自然界被发现以来受到了多方关注,其与胰腺癌的关系也得到了比较深入的研究。黄酮类化合物天然、低毒性,并且对胰腺癌有明显的抑制作用,为一种比较有前景的天然抗胰腺癌药物。在本文中作者首先简要介绍人类胰腺癌的现状,然后介绍了近年来发现的对胰腺癌有抑制作用的黄酮类化合物及其诱导胰腺癌细胞凋亡的机制、导致胰腺癌细胞周期阻滞的原因、对胰腺癌干细胞的抑制作用,并简要评论黄酮类化合物的发展前景。

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