Objective   To evaluate the clinical value,advantages,applicability,short and long term results of interventional endovascular treatment using percutaneous transluminal angioplasty(PTA)and stents for Budd-Chiari syndrome.Methods   Twenty-two cases of Budd-Chiari syndrome were treated with PTA and stents.The obstructive inferior vena cava was dilated by percutaneous transluminal balloon first,and then self-expanding stents was placed.Results  All of operations were successful.Significantly,the pressure of inferior vena cava decreased immediately[(2.68±0.33)-kPa vs (1.52±0.40)-kPa].The symptoms and signs disappeared or relieved after operation in one week and no serious related complications such as heart dysfunction occurred.Follow-up for 6-18 months revealed that the clinical symptoms and signs still improved,and each parameters of liver function were better than those before operation.It reveals that the short and long term results were gratifying,except that only one patient occurred restenosis who underwent the reoperation.Conclusion  Compared with surgery,the interventional endovascular procedure has the advantage of lower cost,less complications and mortality.PTA,stents and anticoagulant are safe and effective treatment in Budd-Chiari syndromes.