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362名脂肪肝患者相关指标及相关疾病患病状况研究
作者:陈文玉1 殷晓勇1 孙桂菊2 张勇2 徐华珠2 潘莹宇2 
单位:1.南京大学医学院附属鼓楼医院体检中心,江苏,南京,210008; 2.东南大学公共卫生学院营养与食品卫生系,江苏,南京,210009
关键词:脂肪肝 血脂 血糖 体质指数 血压 
分类号:P575.5
出版年·卷·期(页码):2004·23·第六期(397-400)
摘要:

目的:探讨脂肪肝患者血清相关生化指标的变化以及高血压、肥胖和糖尿病的发生率.方法:收集来自鼓楼医院体检中心362名脂肪肝患者的体检资料,并与362名健康体检者(为对照组,年龄相差不超过3岁)的资料进行比较.结果:脂肪肝患者体质指数(BMI)高于对照组,同时血清中甘油三酯、总胆固醇、低密度脂蛋白胆固醇、载脂蛋白B、空腹血糖、丙氨酸转氨酶含量及血压(收缩压及舒张压)均值均高于对照组,而高密度脂蛋白胆固醇含量低于对照组.脂肪肝患者高血压、高血糖和肥胖的发生率高于对照组.结论:脂肪肝的发生不仅与脂质代谢紊乱有关,与血糖、血压及BMI间也有联系,脂肪肝患者高血压、糖尿病、肥胖症的患病率高于健康人.

Objective  To explore the changes of the serum inde xes related to fatty liver an d the prevalence rates of the high blood pressure, obesity, and diabetes of the  patients with fatty liver. Methods  Physical examination data of  362 patients with fatty liver were collected in the Drum Tower hospital health  examination center.  These data were compared with the health examination data of 362 non-fatty live r people of  sex-and age matched within 3 years according to the  fatty liver cases. Results  The body mass index (BMI) of the fa tty liver group  was significantly higher than that of normal group.  Meanwhile the differences  of triglycerides (TG), total cholesterol (TCH), low density lipoprotein choleste rol (LDL-C), apolipoprotein B (Apo B), the blood glucose in empty stomach, alan ine aminotransferase (ALT), systolic blood pressure (SBP) and diastolic blood pr essure (DBP) between the fatty liver group and control group were significant.  And the high density lipoprotein cholesterol (HDL-C) level of fat ty li ver patients was lower than that of control group.  The prevalence rates of the  high blood pressure, obesity, and diabetes of the patients with fatty liver were high er than that of control people. Conclusions  The occurrence of f atty liver is related not only to the disturbance of lipid metabolism but als o to the blood gl ucose, blood pressure, and BMI.  The prevalence rates of the high blood pressure , obesity, and diabetes of the patients with fatty liver are higher than those o f control people.

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