>
网站首页期刊介绍通知公告编 委 会投稿须知电子期刊广告合作联系我们
最新消息:
用Logistic回归分析评价肝癌筛检模式
作者:周小平1 茆玉顺1 陈启光2 陈建国3 
单位:1.江苏省妇幼卫生保健中心,江苏,南京,210036; 2.东南大学公共卫生学院,流行病学与卫生统计学系,江苏,南京,210009; 3.启东肝癌防治研究所,江苏,启东,226200
关键词:肝癌 筛检 生存期 因子分析 Logistic回归 
分类号:O212.1, R181.2, R735.7
出版年·卷·期(页码):2002·21·第四期(273-276)
摘要:

目的:评价肝癌高危人群周期性筛检模式的效益.方法:将筛检史变量应用因子模型中主成分法转化成彼此独立的综合指标,然后用Logistic回归模型分析综合指标对肝癌病例生存期的影响.结果:3个综合指标均进入Logistic回归模型.结论:该筛检模式可以比临床提早发现病例,这些病例如得到及时治疗,其生存期有望延长.

Objective  To evaluate the benefit of periodic screening mode in high-risk population of primary hepatic carcinoma.Method  First,using of the screening data of high-risk live cancerous population,the variables of screening history were transformed into synthetic indexes which were independent each other when using principal component methods in factor analysis model;Then,the effect of synthetic indexes and liver function index on survival time was analysised with Logistic model.Result  All of the three synthetic indexes entered the Logistic regression model.Conclusion  The screening mode can find cases ahead of the clinic.If these cases have received treatment timely,it is hopeful to prolong their survival time.

参考文献:

[1] EDDY D M. 关于癌症二级预防的概述, 1988(1)
[2] 周小平, 陈启光, 沈其君. 肝癌筛检间隔确定——嵌套病例对照研究. 南京铁道医学院学报1996(4)
[3] 陈峰. 主成分回归分析, 1991(1)
[4] 沈其君, 周小平, 陈启光. 肝癌筛检研究中效益评价病例对照研究方法, 1995(z1)
[5] 陆培新, 陈建国, 陆新华. 甲胎蛋白低浓度对原发性肝癌诊治的临床意义. 中华医学杂志1986(4) 

服务与反馈:
文章下载】【发表评论】【查看评论】【加入收藏
提示:您还未登录,请登录!点此登录
您是第 414390 位访问者


copyright ©《东南大学学报(医学版)》编辑部
联系电话:025-83272481 83272483
电子邮件:
bjb@pub.seu.edu.cn

苏ICP备09058364