[1] 李正红,王丹华,董梅.谷氨酰胺在早产儿肠外营养中的应用研究[J].中国新生儿科杂志,2006,21:139-142.
[2] MATAR P,ROZADOS V R,GERVASONI S I,et al.Th2/Th1 switch induced by a single low dose of cyclophosphamide in a rat metastatic lymphoma model[J].Cancer Immunol Immunother,2002,50(11):588-596.
[3] 荆科.TLR2、4在内毒素血症幼鼠肠损伤的作用机制和谷氨酰胺与肠三叶因子保护机制的研究[D].沈阳:中国医科大学,2007.
[4] KESSEL A,TOUBI E,PAVLOTZKY E,et al.Treatment with glutamine is associated with down-regulation of Toll-like receptor-4 and myeloid differentiation factor 88 expression and decrease in intestinal mucosal injury caused by lipopolysaccharide endotoxaemia in a rat[J]. Clin Exp Immunol,2008,151(2):341-347.
[5] 李薇,郑晓辉,周伟.谷氨酰胺对坏死性小肠结肠炎新生大鼠Toll样受体4的调控[J].中国当代儿科杂志,2011,13(5),419-423.
[6] LARSON S D,LI J,CHUNG D H ,et al.Molecular mechanisms contributing to glutamine-mediated intestinal cell survival[J].Am J Physiol Gastrointest Liver Physiol,2007,293(6):G1262-G1271.
[7] HARRISON O J,MALOY K J.Innate immune activation in intestinal homeostasis[J].J Innate Immun,2011,3(6): 585-593.
[8] McGUCKIN M A,ERI R,SIMMS L A,et al. Intestinal barrier dysfunction in inflammatory bowel diseases[J]. Inflamm Bowel Dis,2009,15(1):100-113.
[9] FAN J,MENG Q,GUO G,et al.Effects of enteral nutrition supplemented with glutamine on intestinal mucosal immunity in burned mice[J]. Nutrition,2009,25(2): 233-239.
[10] 邓志云,郭光华,杨毅.早期肠内谷氨酰胺补给对烫伤大鼠肠黏膜细胞紧密连接的影响[J].世界华人消化杂志,2009,17(20):2031-2036
[11] 周伟,郑晓辉,荣箫.谷氨酰胺对坏死性小肠结肠炎新生大鼠的保护作用[J].实用儿科临床杂志,2010,25(11):856-859.
[12] 沈通一,秦环龙.谷氨酰胺对肠屏障功能保护作用的研究进展[J]. 肠外与肠内营养,2003,10(3):177-180.
[13] 邵肖梅,叶鸿瑁,丘小汕.实用新生儿学[M].北京:人民卫生出版社,2011:477-483.
[14] WIGHT N E.Donor human milk for preterm infant[J].J Perinatol,2001,21(4):249-254.
[15] BORTHAKUR A,BHATTACHARYYA S,ALREFAI W A,et al.Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent[J].Inflamm Bowel Dis,2010,16(4): 593-603.
[16] 贾盛华,韦红,余加林,等.姜黄素对新生大鼠坏死性小肠结肠炎的保护作用[J].中国当代儿科杂志,2010,12(2):132-136.
[17] MAYNARD A A,DVORAK K,KHAILOVA L,et al.Epidermal growth factor reduces autoghagy in intestinal epithelium and in the rat model of necrotizing enterocolitis[J].Am J Physiol Gastrointest Liver Physiol,2010,299(3):G614-G622.
[18] 王红,夏萍,王凤敏,等.早产儿坏死性小肠结肠炎血乳酸及肿瘤坏死因子-α 测定的临床意义[J].中国新生儿科杂志,2013,28(1):39-41.
[19] MANNOIA K,BOSKOVIC D S,SLATER L,et al.Necrotizing enterocolitis is associated with neonatal intestinal injury[J].J Pediatr Surg,2011,46(1):81-85.
[20] NANTHAKUMAR N N,FUSUNYAN R D,SANDERSON I,et al.Inflammation in the developing human intestine: a possible pathophysiologic contribution to neorotizing enterocolitis[J].Proc Natl Acad Sci USA,2000,97(11):6043-6048.
[21] NANTHAKUMAR N,MENG D,GOLDSTEIN A M,et al. The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innateimmune response [J].PLoS One,2011,6(3):el7776.
[22] CLAUD E C.Neonatal necrotizing enterocolitis-inflammation and intestinal immaturity[J].Antiinflamm Antiallergy Agents Med Chem,2009,8(3):248-259.
[23] JIANG P,SANGILD P T,SIGGERS R H,et al. Bacterial colonization affects the intestinal proteome of preterm pigs susceptible to necrotizing enterocolitis[J].Neonatology,2011,99(4):280-288.
[24] SIGGERS R H,SIGGERS J,THYMANN T,et al.Nutritional modulation of the gut microbiota and immune system in preterm neonates susceptible tonecrotizing enterocolitis[J].J Nutr Biochem,2011,22(6):511-521.
[25] BLACK A,BHAUMIK S,KIRKMAN R L,et al.Developmental regulation of Th17-cell capacity in human neonates[J].Eur J Immunol,2012,42(2):311-319.
[26] BETTELLI E,CARRIER Y,GAO W,et al.Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells[J].Nature,2006,441(7090):235-238.
[27] CHAN K L,WONG K F,LUK J M.Role of LPS /CD14 /TLR4-mediated inflammation in necrotizing enterocolitis:pathogenesis and therapeutic implications[J].World J Gastroenterol,2009,15(38):4745-4752.
[28] SMITH S D,CARDONA M A,WISHNEV S A,et al.Unique characteristics of the neonatal intestinal mucosal barrier[J].J pediatr Surg,1992,27(3):333-336.
[29] LACEY J M,CROUEH J B,BENFELL K,et al.The effects of glutamine supplemented parenteral nutrition in premature infants[J].JPEN J Parenter Enteral Nutr,1996,20(l):74-80.
[30] BOBER-OLESINSKA K,KORNACKA M K.Effeets of lutamine supplamented parenteral nutrition on the incidence of necrotizing enterocolitis,nosocomial sepsis and length of hospital stay in very low birth weight infants[J].Med Wieku Rozwoj,2005,9(3Pt1):325-333. |
