Objective:To investigate the clinical characteristics of infection among patients with multiple myeloma (MM). Methods:A total of 268 cases of MM hospitalized patients were retrospectively analyzed from March 2015 to August 2016. Results:Forty-two patients (19.4%) suffered from nosocomial infections pathogens mainly derived from the respiratory tract (59.2%). Fungi (Candida albicans) and Gram-negative bacilli accounted for 35.3% respectively, and Gram-positive cocci accounted for 23.5%. At the same time patients who were infected from hospital also got pathogens from the respiratory tract very often (77.8%). Gram-positive cocci accounted for 37%, Gram-negative bacilli accounted for 40.7%, and fungi accounted for 18.5%. High ECOG score at admission (≥ 2 points), and hypoalbuminemia were high risk factors for nosocomial infection in patients with myeloma. Conclusion:There is a high risk of nosocomial infection in patients with multiple myeloma, and infection is related to many factors. But through the rational use of antibiotics, as well as predictive means of prevention and control, we may reduce the intensity of infection, and reduce the incidence of nosocomial infection. |
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