Objective: To explore clinical value of the ultrasound on the diagnosis and manual reduction of uterine inversion. Methods: Ultrasonic manifestations, clinical data and process of the clinical physicians manual reduction uterine inversion guided by ultrasound in a patient who was clinically confirmed to be uterine inversion was analyzed and the relevant literature was reviewed. Results: Two-dimensional sonographic findings of uterine inversion:longitudinal section of the uterine showed that the bottom of uterine was sagged, uterine cavity line was disappeared, zonal middle echoes which included thin low echoes was found in the centre of uterus;Uterine cross section showed that different echo presented a circular permutation. Color Doppler flow imaging:rich signal of blood flow relatively gathered was found in central of uterus. Manual restoration by clinician was successfully under the guiding of ultrasound. Conclusion: Ultrasonography not only can diagnose uterine inversion but also can whole process real-time monitoring and effective guidance the clinicians to restore the varus uterus through vaginal manipulation. Ultrasound has an important clinical value during the diagnosis and guiding manual reduction.