SF-36和EQ-5D量表在慢性肾脏病患者生命质量评估中的对比研究-东南大学学报医学版

SF-36和EQ-5D量表在慢性肾脏病患者生命质量评估中的对比研究

单位：1. 徐州医科大学临床医学系, 江苏徐州 221004;
2. 徐州医科大学公共卫生学院, 江苏徐州 221004;
3. 新乡医学院基础医学院, 河南新乡 453003;
4. 徐州市中心医院肾脏内科, 江苏徐州 221009

分类号：R195.1

出版年·卷·期（页码）：2019·38·第六期（1024-1028）

摘要：

目的：比较健康状况调查简表（SF-36）和五维度欧洲生命质量量表（EQ-5D）对慢性肾脏病患者生命质量的评价效果。方法：采用SF-36和EQ-5D量表对徐州市中心医院112例慢性肾脏病患者入院和出院时的生命质量进行评估，比较EQ-5D的视觉标尺评分（EQ-VAS）和SF-36总分、生理总测量（PCS）和心理总测量（MCS）评分的均值、z标准分。结果：112例患者EQ-VAS评分出院时（0.72±0.20）高于入院时（0.58±0.20）（P < 0.05），出院时患者SF-36总分、PCS评分和MCS评分依次为（60.75±23.16）、（59.84±23.59）和（61.65±25.17）分，高于入院时的（41.86±21.65）、（42.26±20.98）和（41.46±24.13）分（P < 0.05）。EQ-VAS出入院z标准分的差值（0.8278）高于SF-36 z标准分的差值（0.7781）（P < 0.05）。EQ-VAS评分与SF-36总分、PCS、MCS总评分的Pearson相关系数分别为0.555、0.534、0.532（P < 0.01）。对应分析显示EQ-VAS的区分度优于SF-36总分。结论：EQ-5D和SF-36量表均能评价慢性肾脏病患者的生命质量，EQ-VAS评分的反应度、区分度高于SF-36，EQ-VAS更简单方便，是慢性肾脏病患者生命质量评价的有效工具。

Objective: To compare the effect of Short Form 36(SF-36) and Five-Dimensional Euro Quality of Life (EQ-5D) on the quality of life for patients with chronic kidney disease. Methods: One hundred and twelve patients with chronic kidney disease in Xuzhou Central Hospital were assessed by SF-36 and EQ-5D scales at admission and discharge. EQ-5D visual scale (EQ-VAS) and SF-36, physical component summary(PCS) and mental component summary (MCS) scores, as well as the standardized zscores were compared. Results: The mean of EQ-VAS score of the 112 patients at discharge (0.72 +0.20) was higher than that of admission (0.58 +0.20) (P < 0.05). The total score of SF-36, PCS and MCS of discharged patients were 60.75 +23.16, 59.84 +23.59 and 61.65 +25.17, respectively, which were higher than those of admission (41.86 +21.65, 42.26 +20.98 and 41.46 +24.13) (P < 0.05). The z standardized score difference of EQ-VAS (0.8278) was higher than that of SF-36 (0.7781) (P < 0.05). The correlation coefficients between EQ-VAS score and SF-36 score, PCS score and MCS score were 0.555, 0.534 and 0.532, respectively (P < 0.01). Correspondence analysis showed that the EQ-VAS score was better than the SF-36 total score. Conclusion: Both EQ-5D and SF-36 scales can evaluate the quality of life for patients with chronic kidney disease. EQ-VAS score is more appropriate than SF-36 due to its high capacity of reactivity and discrimination. EQ-VAS is an effective tool for evaluating the quality of life for patients with chronic kidney disease.

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