Objective:To explore the value of ultrasonography in the diagnosis of intraductal papilloma. Methods:Color Doppler sonography and contrast-enhanced ultrasonography of 62 lesions in 51 patients with intraductal papilloma confirmed by surgical pathology were retrospectively analyzed. Results:The contrast-enhanced ultrasonography of intraductal papilloma of the mammary gland was characterized by high enhancement, uniform distribution of contrast agents, regular morphology after enhancement, and clear edge. 61(98.4%,61/62) lesions showed high enhancement after sonography, 46(74.2%,46/62) lesions had clear edges after sonography, and 33(53.2%,33/62) lesions showed no significant change in the range of enhancement after sonography compared with the range of two-dimensional ultrasound images. The contrast-enhanced time (RT), peak intensity (PI), area under the curve (AUC), and peak time (TTP) of intraductal papilloma lesions of the mammary gland were statistically significant compared the peripheral glands (P<0.05). Conclusion:There is limited specificity in both two-dimensional ultrasound images and contrast-enhanced ultrasonography when diagnosing intraductal papilloma, however, the combination of the two methods can be quite helpful to improve the detection rate and diagnostic accuracy of the lesions. |