江苏省六地心血管病高危人群腰身比与颈动脉异常的相关性分析-东南大学学报医学版

江苏省六地心血管病高危人群腰身比与颈动脉异常的相关性分析

单位：1. 常熟市疾病预防控制中心慢性病防制科, 江苏常熟 215500;
2. 江苏省疾病预防控制中心慢性非传染病防制所, 江苏南京 210009

分类号：R543.4

出版年·卷·期（页码）：2025·44·第二期（183-188）

摘要：

目的:了解江苏省心血管病高危人群腰身比与颈动脉异常之间的关系,为动脉粥样硬化及早期心血管病防治提供借鉴。方法: 依托心血管病高危筛查项目,选取江苏省6个项目点2015年9月至2016年6月筛查出的11 384名心血管病高危人群作为研究对象,对其分别进行问卷调查、体格检查和颈动脉超声检查,探讨腰身比与颈动脉超声异常的关系。结果:江苏省心血管病高危人群颈动脉斑块率为36.7%,江苏省心血管病高危人群中腰身比高的人群颈动脉异常风险为腰身比低的人群的1.10倍(OR=1.10,95%CI 1.00~1.20),颈动脉斑块风险为1.19倍(OR=1.19,95%CI 1.08~1.31)。交互作用结果显示,在江苏省心血管病高危人群中,低密度脂蛋白胆固醇正常人群腰身比对颈动脉斑块的发生风险作用更强(乘交互作用P<0.05)。结论: 江苏省心血管病高危人群中颈动脉斑块检出率较高,腰身比与颈动脉斑块呈正相关。

Objective: To investigate the relationship between waist-to-height ratio and carotid artery abnormalities in high-risk populations for cardiovascular disease in Jiangsu Province, thereby offering scientific evidence for the prevention and treatment of atherosclerosis and early cardiovascular disease. Methods: From September 2015 to June 2016, as part of the National High-risk Population Early Screening Project for Cardiovascular Diseases, 11 384 individuals identified as high-risk for cardiovascular disease from 6 project sites in Jiangsu Province were selected as study subjects. They were subjected to questionnaire, physical examinations, and carotid ultrasound examinations to analyze the relationship between waist-to-height ratio and carotid ultrasound abnormalities. Results: The prevalence of carotid plaque among the high-risk population for cardiovascular disease in Jiangsu Province was determined to be 36.7%. And the risk of carotid artery abnormalities in the high-risk population for cardiovascular disease with a high waist-to-height ratio was 1.10 times that of those with a low waist-to-height ratio(OR=1.10, 95%CI 1.00-1.20), and the risk of carotid artery plaque was 1.19 times(OR=1.19, 95%CI 1.08-1.31). The interaction results indicated that the waist-to-height ratio had a stronger effect on the risk of carotid artery plaque occurrence in non-high/low-density lipoproteinemia populations among the high-risk population for cardiovascular disease in Jiangsu Province(interaction P<0.05). Conclusion: In the high-risk population for cardiovascular disease in Jiangsu Province, a high detection rate of carotid plaque has been observed, and these carotid plaque are found to be positive related to the waist-to-height ratio.

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